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- Acupuncture and Herbal Medicine Treatment in Cancer Care: A Scoping Review Focused on European Regions
- Kwonwoo Park, Jeong Su Park, Minji Kim, Gyumi Park, Yujin Lee, Hakyung Lee
- Perspect Integr Med. 2025;4(3):131-140. Published online October 22, 2025
- DOI: https://doi.org/10.56986/pim.2025.10.002
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- Acupuncture and herbal medicine have traditionally been used in East Asia for cancer care. This study aimed to explore how acupuncture and herbal medicine in cancer treatment is used in Europe to identify the common cancer types treated, therapeutic methods applied, and patient satisfaction. This scoping review followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews guideline and Arksey and O’Malley’s methodological framework. Literature searches were conducted using electronic databases and 2 complementary and alternative medicine-focused journals. The inclusion criteria included first author’s affiliation in Europe and use of acupuncture or herbal medicine in cancer treatment. The exclusion criteria included focusing solely on chemotherapy-related adverse effects or in vitro research. From 6,109 initial records, 6 studies met the inclusion criteria. Two studies involved acupuncture, and 4 involved herbal medicine. Breast cancer was the most frequently studied and ST36 was the most frequently used acupuncture point. Herbal medicines included mistletoe extract and Ruta graveolens. Reported outcomes included symptom relief and generally positivity, although findings varied. This scoping review identified a limited but emerging body of cancer research on the use of acupuncture and herbal medicine in Europe. Highquality clinical research is needed.
- Minimum Clinically Important Difference for Nonsurgical Interventions for Spinal Diseases: Choosing the Appropriate Values for an Integrative Medical Approach
- Ye-Seul Lee, Sungmin Lee, Yoon Jae Lee, In-Hyuk Ha
- Perspect Integr Med. 2023;2(2):86-99. Published online June 23, 2023
- DOI: https://doi.org/10.56986/pim.2023.06.003
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- 9 Citations
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- The minimal clinically important difference (MCID) plays a crucial role in the design and interpretation of clinical trials, as it helps in distinguishing between statistically significant and clinically meaningful outcomes. This scoping review aims to collate and appraise the current research concerning the validation of MCIDs for surgical and nonsurgical measures for spine disorders. Two databases of MEDLINE (PubMed and EMBASE) were searched. There were 1,590 studies retrieved and 79 were selected as eligible for review. Measurement tools such as the Oswestry Disability Index, Neck Disability Index, Numeric Rating Scale, and Visual Analogue Scale were assessed by regions and interventions. A total of 24 studies identified MCIDs on nonsurgical interventions, and 55 studies identified MCIDs on surgical interventions. The range of MCIDs varied greatly depending on study population, specific interventions, calculation methods, and outcomes. This scoping review emphasizes the complexity and variability in determining MCIDs for musculoskeletal or neurodegenerative spinal diseases, influenced by several factors including the intervention type, measurement tool, patient characteristics, and disease severity. Given the wide range of reported MCIDs, it is crucial to consider the specific context when interpreting these values in clinical and research settings. To select an appropriate MCID value for comparison in a clinical trial, careful consideration of the patient group, intervention, assessment tools, and primary outcomes is necessary to ensure that the chosen MCID aligns with the research question at hand.
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- Efficacy and safety of musculoskeletal manipulations in elderly population with musculoskeletal disorders: a systematic review
Donatella Bagagiolo, Michela Persiani, Luca Cicchitti, Luca Vismara, Irene Bruini, Alessandro Mauro, Francesca Buffone
BMJ Open.2025; 15(6): e088655. CrossRef - Predicting nonsurgical treatment outcomes in lumbar disc herniation: leveraging sparse electronic health records for patient phenotyping
Ye-Seul Lee, Yoon Jae Lee, In-Hyuk Ha
International Journal of Medical Informatics.2025; 204: 106056. CrossRef - Minimal Clinically Important Difference in Patients with Acute Neck Pain Undergoing Conservative Treatment with Korean Medicine
Ji Sun Kim, Eunsan Kim, Seungwon Shin, In-Hyuk Ha, Yoon Jae Lee
Journal of Pain Research.2025; Volume 18: 3709. CrossRef - Minimal Clinically Important Difference in the Self-Measured 6-Minute Walking Test in Patients with Sciatica Undergoing Epidural Steroid Injection
Michal Ziga, Martin N. Stienen, Anna Maria Zeitlberger, Stefanos Voglis, Luca Regli, Oliver Bozinov, Nicolai Maldaner
World Neurosurgery.2025; 202: 124364. CrossRef - A cost-utility analysis of pharmacopuncture versus physiotherapy for chronic low back pain: A multicenter, pragmatic randomized controlled trial
Ye-Seul Lee, Soo Jin Kim, Kyung Sun Park, Yoon Jae Lee, Changsop Yang, Chang-Hyun Han, In-Hyuk Ha
Integrative Medicine Research.2025; 14(4): 101210. CrossRef - A Retrospective Survey and Chart Review of the Effectiveness and Satisfaction of Korean Medicine Treatment at the National Shooting Competition On-Site Medical Clinic
Minwoo Bang, Suyong Shin, Jungsang Kim, Minwhee Kang, Donghun Lee, Junho Kim, Chunghee Kim, Jiyoung Son, Seungyeon Choi, Seonghyeon Jeon, Jeeeun Kim, Seul Yi, Daemyung Lee, Byungsoo Kang
Journal of Korean Medicine Rehabilitation.2025; 35(4): 225. CrossRef - Exploring the Effects of Virtual Reality on Pain Relief and Physical Mobility in Spa-Based Treatment
Alina Huseynli, Vojtěch Špet, Alena Lochmannová, Konstantin Novikov, Ladislav Špišák, Aleš Příhoda
Journal of Clinical Medicine.2025; 14(23): 8510. CrossRef - Minimum clinically important difference and substantial clinical benefit in patients with chronic temporomandibular disorders
Jaemin Son, Eun‐San Kim, Yoon Jae Lee, Nam‐Woo Lee, In‐Hyuk Ha
Journal of Oral Rehabilitation.2024; 51(8): 1468. CrossRef - Safety and effectiveness of integrative Korean medicine for the management of patients sustaining injuries in traffic accidents during pregnancy: A retrospective chart review and questionnaire survey
Dahyun Kyung, Kyoung Sun Park, Ji-Eun Koo, Sujin Kim, Jiwon Park, Jun-Hyo Bae, Jieun Bae, Suna Kim, Yoon Jae Lee, In-Hyuk Ha
Medicine.2024; 103(21): e38250. CrossRef
- Efficacy and safety of musculoskeletal manipulations in elderly population with musculoskeletal disorders: a systematic review
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